Polynucleotide treatments are rapidly becoming one of the most requested skin rejuvenation procedures in London. At Injectual, our advanced injectables studio based in London, we’ve seen firsthand how polynucleotides can completely transform the skin: improving hydration, restoring elasticity, reducing fine lines, and promoting long-term regeneration at a cellular level.
Whether you’ve booked your first appointment or you’re simply researching what to expect, this guide covers everything you need to know about polynucleotide injections. From the healing timeline and aftercare tips to results and frequently asked questions.
What Are Polynucleotide Injections?
Polynucleotides are naturally derived molecules that form the building blocks of DNA. In aesthetic medicine they are used to trigger deep skin regeneration, encourage collagen and elastin production, and reduce inflammation.
The result? Firmer, brighter, and healthier-looking skin with improved elasticity and hydration, all without the need for synthetic fillers.
What Skin Concerns Do Polynucleotides Treat?
At Injectual, we offer polynucleotide treatments for a variety of concerns:
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Fine lines and wrinkles
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Dull, sun-damaged skin
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Rosacea and redness
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Pigmentation and acne scars
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Stretch marks and skin laxity
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Dehydrated or thinning skin
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Under-eye hollows or crepey texture
Polynucleotide treatments can be used on the face, neck, hands, abdomen, décolletage, knees, and even the delicate eye area — making it one of the most versatile anti-ageing treatments available.
What Happens After Polynucleotide Treatment?
Mild swelling, redness or small bumps at the injection sites are all completely normal. These effects usually subside within 24–48 hours, and there is minimal downtime, meaning you can get back to your daily routine quickly — ideal for busy Londoners on the go.
You may notice:
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Slight redness or puffiness
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Tenderness at injection sites
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Tiny, mosquito-bite-like bumps (these flatten within hours)
For most, any visible signs fade quickly and can be easily concealed with makeup after the first day.
Essential Polynucleotide Aftercare Tips
To get the best results from your polynucleotide injections at Injectual, we recommend the following:
1. Skip Makeup for 24 Hours
Let your skin breathe after treatment. While redness is usually mild, it's best to avoid applying cosmetics during the first day.
2. Stay Hydrated & Avoid Heavy Exercise
Drink plenty of water and avoid saunas, steam rooms, and high-intensity workouts for 48 hours. Sweat can introduce bacteria to open injection points and interfere with healing.
3. Use Gentle Skincare Products
Keep your skincare routine simple. Avoid active ingredients like AHAs, BHAs, and retinoids for 48 hours post-treatment.
4. Wear SPF
Always apply a broad-spectrum sunscreen (SPF 30 or higher) to protect your healing skin from UV exposure, especially if walking around central London.
If you experience anything unusual or are unsure about your recovery, contact us for advice.
When Will I See Results from Polynucleotide Injections?
Polynucleotide injections work gradually, encouraging your skin to repair itself from within. Most clients begin noticing improvements in:
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Skin hydration and plumpness within 2–3 weeks
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Brightness and improved texture by week 4
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Visible firmness, smoothness, and elasticity at around 12 weeks
These results continue to improve over time, with many clients reporting youthful, refreshed skin that lasts up to 6 months or more.
How Many Treatments Will I Need?
At Injectual, we typically recommend a course of three polynucleotide treatments, spaced four to six weeks apart for optimal results.
Your treatment plan will be personalised based on:
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The area(s) you want to treat
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The condition of your skin
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Your desired outcomes
Maintenance sessions are usually advised once or twice a year to keep your skin looking fresh and rejuvenated.
Is the Treatment Painful?
Polynucleotide treatments are well tolerated by most patients. You may feel a light pinching or stinging sensation, but it’s generally mild and very quick. If you’re concerned about discomfort, a numbing cream can be applied beforehand.
Why Choose Injectual for Polynucleotide Injections in London?
Injectual is an advanced aesthetic clinic located in the heart of London, known for expert-level injectable treatments and a holistic approach to facial aesthetics. We specialise in achieving natural-looking, long-lasting results without overdoing it.
Whether you're looking to soften fine lines, refresh tired skin, or improve texture around the eyes — our team will guide you through your personalised polynucleotide journey.
Book Your Polynucleotide Consultation at Injectual in London
Ready to experience the skin-rejuvenating power of polynucleotides? Contact us now to book your appointment and discover why polynucleotides are the future of anti-ageing skincare.
FAQs About Polynucleotide Treatments at Injectual London
1. How long is the appointment?
Treatment typically takes 30 minutes – perfect for fitting into a busy London day.
2. Who is it suitable for?
Polynucleotide treatments are safe for most skin types. However, those with active skin infections or autoimmune conditions should consult with a practitioner first.
3. How is it different from fillers?
While dermal fillers add volume, polynucleotides work on a cellular level to improve skin quality and stimulate natural regeneration.
