The Injectual Polynucleotide Cocktail XL

£595.00
£595.00
Sensitive Skin Rosacea Dull Skin Acne
GET £100 OFF YOUR 1ST TREATMENT

We just know you'll love your treatment with us so we're giving you £100 off your 1st treatment (over £300). Book your complimentary consultation below to start your aesthetic journey.

GET £100 OFF YOUR 1ST TREATMENT

We just know you'll love your treatment with us so we're giving you £100 off your 1st treatment (over £300). Book your complimentary consultation below to start your aesthetic journey.

GET £100 OFF YOUR 1ST TREATMENT

We just know you'll love your treatment with us so we're giving you £100 off your 1st treatment (over £300). Book your complimentary consultation below to start your aesthetic journey.

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Advanced Regenerative Skin Rejuvenation in London

The Injectual Polynucleotide Cocktail XL is our most advanced regenerative injectable treatment, designed to restore skin quality, resilience, and radiance at a cellular level. This enhanced protocol combines multiple polynucleotide formulations with skin-boosting actives to deliver intensive tissue repair, collagen stimulation, and long-term skin health, without adding volume.

Developed and refined by Injectual, the Polynucleotide Cocktail XL represents a next-generation approach to aesthetic medicine, prioritising biological skin regeneration, skin strength, and longevity.

What Is the Injectual Polynucleotide Cocktail XL?

The Injectual Polynucleotide Cocktail XL is a medical-grade injectable protocol that activates the skin’s natural regenerative processes. It uses highly purified polynucleotides, derived from DNA fragments, to stimulate fibroblast activity, enhance collagen and elastin production, and improve overall skin integrity.

The XL protocol delivers a higher regenerative impact by combining multiple polynucleotide products in a single treatment session, making it particularly effective for advanced skin ageing, compromised skin quality, and intensive rejuvenation.

What’s Included in the Polynucleotide Cocktail XL?

PLINEST® Polynucleotides (Eyes & Skinbooster)

At the core of the Polynucleotide Cocktail XL are PLINEST® Eyes and PLINEST® Skinbooster, clinically established polynucleotide injectables used extensively in regenerative and aesthetic medicine.

These polynucleotides work by:

  • Stimulating fibroblast activity

  • Enhancing collagen and elastin synthesis

  • Accelerating tissue repair and regeneration

  • Improving firmness, elasticity, and hydration

  • Strengthening the skin barrier

PLINEST Eyes is designed for delicate areas, while PLINEST Skinbooster targets larger areas requiring structural skin improvement.

NEWEST® by Dermafocus

The XL protocol also incorporates NEWEST® by Dermafocus, which enhances hydration, skin density, and luminosity. Used alongside polynucleotides, it supports the regenerative environment and improves overall skin texture and radiance.

Injectual Proprietary Nutrient Blend

To maximise outcomes, the Polynucleotide Cocktail XL includes a bespoke Injectual blend of essential nutrients, including vitamins, amino acids, and hyaluronic acid. This proprietary formulation is designed to support collagen production, improve skin quality, and promote long-term skin health.

Polynucleotides & “Salmon Sperm” Treatments: What You Should Know

Polynucleotide treatments are often referred to online as “salmon sperm facials.” This is a consumer-led term used to describe regenerative treatments derived from fish DNA.

At Injectual, the Polynucleotide Cocktail XL uses highly purified polynucleotides derived from trout DNA, not salmon. Trout DNA is chosen for its high biocompatibility with human skin, excellent safety profile, and proven regenerative properties.

These DNA fragments are extensively purified and processed to ensure they are safe, sterile, and suitable for medical aesthetic use. The resulting polynucleotides work by:

  • Supporting cellular repair and regeneration

  • Stimulating collagen and elastin production

  • Improving skin resilience and texture

While the “salmon sperm” term is commonly used in popular media, the science behind the treatment is polynucleotide therapy, and the clinical results are based on regenerative medicine—not cosmetic trends.

What Skin Concerns Does the Polynucleotide Cocktail XL Treat?

The Injectual Polynucleotide Cocktail XL is particularly effective for:

  • Dull, tired, or stressed skin

  • Fine lines and early to moderate signs of ageing

  • Loss of firmness and elasticity

  • Dehydrated or compromised skin

  • Uneven texture and tone

  • Skin requiring intensive repair or rejuvenation

It is ideal for clients seeking natural, progressive skin improvement without fillers or volumisation.

Treatment Areas

  • Face

  • Neck

  • Jowls

  • Hands

  • Hairline and scalp (to support hair quality and growth)


Results: What to Expect

The Polynucleotide Cocktail XL delivers progressive, regenerative results. Clients typically experience:

  • Improved hydration and luminosity within the first few weeks

  • Enhanced skin texture, firmness, and density

  • Increased elasticity and resilience over time

  • Healthier, stronger, more radiant skin

As this is a regenerative treatment, results continue to improve as collagen production and tissue repair processes are activated.

Treatment Plan & Course Recommendations

The Injectual Polynucleotide Cocktail XL can be performed as a stand-alone treatment, however for optimal regenerative results, a course of three treatments is recommended.

  • Frequency: Every 2–4 weeks

  • Maintenance: Periodic top-up treatments may be advised

Your clinician will tailor the treatment plan following a full consultation and skin assessment.

Why Choose Injectual for Polynucleotide Treatments?

  • Medically led, evidence-based protocols

  • Advanced expertise in polynucleotide and regenerative therapies

  • Focus on long-term skin health and quality

  • Bespoke treatment planning

  • Premium products and rigorous safety standards

Injectual is recognised for delivering refined, clinically driven aesthetic outcomes.

FAQs – Injectual Polynucleotide Cocktail XL

Is this the same as a salmon sperm facial?

This treatment is often grouped under the term “salmon sperm facial,” but the Injectual Polynucleotide Cocktail XL uses polynucleotides derived from trout DNA, which are medically processed and purified for safe aesthetic use.

Why is trout DNA used?

Trout DNA offers excellent biocompatibility, stability, and regenerative properties, making it highly suitable for medical aesthetic treatments.

Is the Polynucleotide Cocktail XL a filler?

No. This treatment does not add volume or change facial structure. It improves skin quality and strength from within.

Is there downtime?

Minimal downtime. Mild redness, swelling, or small injection marks may occur and typically resolve within a few days.

When will I see results?

Hydration and glow may appear within 2–3 weeks. Regenerative improvements develop progressively over several weeks.

Is the treatment safe?

Yes. All products used are medical-grade and administered following full consultation and medical screening.

Who is not suitable?

Not suitable during pregnancy or breastfeeding, or for certain medical conditions. Suitability is confirmed during consultation.

Book a Polynucleotide Cocktail XL Consultation

To find out whether the Injectual Polynucleotide Cocktail XL is right for you, book a personalised consultation with our medical team. We will assess your skin, discuss your goals, and design a bespoke regenerative treatment plan.


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OUR INJECTUAL PRACTITIONERS

Dr
FOUNDER PLASTIC SURGEON DR. VEERLE
Our founder Dr. Veerle, MD, FEBOPRAS, FCCP, is one of London's leading female plastic surgeons and is the co-founder of London’s holistic clinic, Tempus Belgravia. As her favourite motto is 'To be the best you need to learn from the best', Dr. Rotsaert has been travelling the world on the hunt for the world's leading techniques. Her and her peers' knowledge and skill have been used to create 5 proprietary techniques that will be used in all INJECTUAL clinics and by all injectors. 

 As founder of Injectual, Dr Rotsaert’s knowledge and understanding of both the surgical and non-surgical landscape is invaluable, and her commitment to helping enhance her patients’ lives continues to inspire.
Dr
AESTHETIC DOCTOR
TONY

Dr. Tony, a University of Nottingham graduate in Genetics and Biochemistry, pursued medical training at the University of Liverpool passing with merit. He comes with a wealth of experience: he has 8 years experience in Surgical Specialties in the NHS and 5 years in Aesthetic Medicine. 

He is also an Aesthetics Trainer for a large training academy where he trains other medical practitioners how to become safe and confident injectors. He offers a vast range of treatments, from anti-wrinkle treatments to dermal fillers, injectable skincare (e.g. Profhilo, polynucleotides), microneedling, as well as holistic skincare consultations and chemical peels. 

 Specialities: Non-surgical nosejobs, skinboosters, masculinisation + skincare
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AESTHETIC PHARMACIST
ZAIN

Zain Ali is a dynamic pharmacist with a new approach to aesthetics, blending his deep pharmaceutical knowledge with a passion for skincare. After earning his Master’s degree in Pharmacy (mPharm) in 2018, Zain became an independent prescriber. 

Zain’s journey in aesthetics began in 2021, fueled by years of experience in luxury skincare and a desire to elevate his clients’ confidence through personalised treatments. He specialises in cutting-edge procedures, including, polynucleotides, and skin boosters, always staying at the forefront of the industry’s latest advancements. 

Specialities: Facial feminisation, injectual polynucleotide cocktail, skinboosters, anti-wrinkle treatments and medical grade skincare
Dr
AESTHETIC DOCTOR
NINA

Dr. Nina Cunning, a skilled injector and aesthetic practitioner, holds a Bachelor of Science in Medicine and Bachelor of Medicine and Bachelor of Surgery (MBChB) from The University of St Andrews and The University of Glasgow. With expertise in Head and Neck Surgery, she completed prestigious training and a two-year fellowship in Robotic Head and Neck Surgery in London. Actively engaged in international aesthetics conferences, she crafts bespoke aesthetic experiences, blending skill with a personable demeanor for transformative client journeys. 

Specialities: Advanced facial contouring, lip enhancements, polynucleotides + The Injectual Polynucleotide Cocktail
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AESTHETIC NURSE
LYDIA

Nurse Lydia is a highly skilled registered nurse prescriber and aesthetic practitioner at Injectual, specialising in polynucleotides, lip enhancements, and anti-wrinkle treatments. With extensive experience in the field, Lydia is passionate about delivering regenerative treatments that provide subtle yet transformative results.

She holds a prestigious Level 7 diploma in clinical aesthetic injectable therapies and has trained under internationally renowned consultant plastic surgeons, ensuring her clients receive the highest standard of care and expertise.

Specialities: (Under eye) polynucleotides, Artistic Transformations, lip enhancement and anti-wrinkle treatments


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AESTHETIC NURSE
ROBYN

Nurse Robyn is a highly skilled Aesthetic Nurse with 9 years of experience in providing a wide range of aesthetic treatments. With a strong background in both clinical and cosmetic procedures, she specialises in delivering personalised care that enhances natural beauty and boosts client confidence. Robyn is proficient in advanced techniques such as injectables (Anti-wrinkle treatment, dermal fillers and skin boosters) and skin rejuvenation therapies. Her ethos is attention to detail and a compassionate approach, she strives to achieve exceptional results by discussing patient expectations and developing an individualised treatment plan.

Specialities: under eye enhancement + lip filler
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AESTHETIC DOCTOR
Fiori Teklebrhan
Dr. Fiori Teklebrhan is an experienced aesthetic doctor and skilled injector. She holds an MBBS, a First-Class Honours BSc in Psychology, and a Distinction in Aesthetic Medicine from Queen Mary University of London. Since specializing in aesthetics full-time in 2022, Dr. Fiori has completed over 1,500 injectable treatments, focusing on natural results that enhance confidence.

Her expertise includes advanced toxin, dermal fillers, skin boosters, and polynucleotides. With a background in breast surgery and anatomy teaching, she combines medical precision with a holistic approach. Committed to ethical, patient-centered care, Dr. Fiori develops bespoke treatment plans emphasizing subtle enhancement and long-term well-being. She is passionate about midface and lower face sculpting and champions regenerative treatments for skin radiance and health. 

Specialities: Midface and lower face sculpting with dermal filler, skin brightening with polynucleotides and skin boosters.
GET £100 OFF YOUR 1ST TREATMENT

We just know you'll love your treatment with us so we're giving you £100 off your 1st treatment (over £300). Book your complimentary consultation below to start your aesthetic journey.

INJECTUAL NOTTING HILL

59 WESTBOURNE GROVE, LONDON  


Mon - Saturdays: 10am - 6pm

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149 COMMERCIAL STREET, LONDON  


Mon - Saturdays: 10am - 6pm

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