Dark circles. Tired eyes. Under-eye hollows. Call them what you like, but they all point to the same problem: your eyes don’t match how you feel. Whether it’s genetics, lack of sleep, or the unavoidable pull of time, the under-eye area is often the first to go.
At Injectual, London’s go-to aesthetic clinic, we offer a range of evidence-based treatments to tackle dark circles at the source. Not just cover them up. Here’s what’s actually worth your time and money.
1. Polynucleotides
What it is:
Polynucleotides are DNA fragments derived from salmon sperm. It sounds weird. But it works. These molecules are potent skin regenerators, boosting collagen, improving microcirculation, and calming inflammation.
How it helps with dark circles:
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Increases collagen and elastin for firmer under-eye skin
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Enhances blood flow, reducing pigmentation and puffiness
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Improves lymphatic drainage, tackling under-eye bags
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Strengthens the skin barrier, making skin look brighter and more even
2. Tear Trough Fillers
What it is:
Traditional hyaluronic acid fillers can restore volume under the eyes, reducing shadows caused by hollowness. Think of it as structural support under your skin.
Benefits:
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Instant results after just one session
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Replaces lost volume that contributes to a “sunken” look
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Smooths hollows and softens shadows
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Lasts up to 12 months
3. Combination Therapy: Polynucleotides + Microneedling
This is where Injectual shines. We don’t just pick a treatment and hope it works. We combine approaches for layered results. Our combo of microneedling and polynucleotide injections delivers:
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Deeper product penetration
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Faster collagen stimulation
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Improved texture and hydration
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Enhanced elasticity and brightness
Microneedling acts like an accelerator, boosting absorption and kickstarting your skin’s natural repair mechanisms.
4. Plinest (Polynucleotide) Under-Eye Rejuvenation
Plinest is one of the most powerful under-eye skinboosters available. Unlike fillers, which add volume, Plinest rebuilds your skin from the inside out.
How it works:
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Stimulates fibroblasts to produce new collagen and elastin
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Improves microcirculation to reduce pigment buildup
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Promotes cellular renewal and tissue regeneration
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Contains antioxidants to protect against free radicals
Comparing Under-Eye Treatments
Treatment |
Best For |
Results Timeline |
Longevity |
Downtime |
Polynucleotides (PlinestAmeela®) |
Pigmentation, fine lines, puffiness |
Gradual, within weeks |
Long-lasting |
Minimal |
Tear Trough Fillers |
Hollowing, volume loss |
Immediate |
9–12 months |
Mild |
Combination Therapy |
Texture, elasticity, stubborn cases |
Progressive |
Long-lasting |
Minimal |
Laser Therapy (not offered by Injectual) |
Pigmentation, texture |
Gradual |
Long-lasting |
Moderate |
Why Clients Choose Injectual for Dark Circles
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85% of our under-eye treatments now involve polynucleotides—because they work.
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We use Plinest, a top-tier polynucleotide filler, backed by science and real results.
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Our combination treatments deliver both cosmetic and biological improvements.
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Practitioners with clinical expertise who won’t overtreat or oversell.
Our goal is subtle, healthy-looking results that don’t scream “I had something done.” Clients walk out looking rested, not altered.
Is Polynucleotide Treatment Right for You?
Best suited for people who:
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Struggle with persistent dark circles or puffiness
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Have sensitive skin or are filler-averse
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Want long-term results, not just a quick fix
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Prefer a natural, regenerative approach
Avoid if you:
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Are pregnant or breastfeeding
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Have an active skin infection in the treatment area
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Have a history of severe allergic reactions
Book Your Under-Eye Consultation at Injectual
If you’re serious about fixing your dark circles instead of covering them, Injectual is the place to start. Whether you need structure, regeneration, or both, we’ll build a personalised plan based on what your skin actually needs. Book a call now.
FAQs
What’s the difference between fillers and polynucleotides?
Fillers add volume. Polynucleotides improve skin quality, tone, and texture over time. They can be used together for best results.
How many sessions will I need?
Usually 2–3 for polynucleotides, spaced a few weeks apart. Fillers often need just one session.
When will I see results?
Polynucleotide results build gradually. You may notice brighter, more hydrated skin after 1–2 weeks, with continued improvement over 1–3 months.
Do polynucleotides hurt?
Discomfort is minimal. We use a numbing cream before injections to keep things comfortable.
Is there any downtime?
Some redness or mild swelling is normal. Most clients return to their routine the same day or next.