It is one of the most common questions we get. You have done your research, you know you want both, and you are wondering whether you need to spread them across two appointments or whether they can be done together.
The short answer is yes. Not only can microneedling and polynucleotides be performed in the same session, combining them is often the point.
Why They Work Well Together
Microneedling creates thousands of controlled micro-channels in the skin using fine needles. This triggers the skin's healing response, stimulating collagen and elastin production. It also does something else that is clinically useful: it opens the skin to deeper absorption of any active ingredients applied immediately after.
Polynucleotides are highly biocompatible molecules derived from purified DNA. They support cell repair, stimulate fibroblast activity, and improve hydration at a structural level. Applied into freshly needled skin, their absorption and efficacy is significantly enhanced compared to application on intact skin.
The result is a treatment where each element amplifies the other. Microneedling drives the physical renewal. Polynucleotides support and accelerate the biological repair that follows.
What the Combination Treats
At Injectual, the under eye microneedling and polynucleotides treatment is designed specifically for one of the most difficult areas to treat on the face. The skin under the eye is thin, delicate and highly vascular, which makes it prone to dark circles, puffiness, fine lines and loss of elasticity.
The combination addresses all of these concerns in a single session:
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Dark circles, improved through better circulation and reduced vascular visibility
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Under-eye puffiness, reduced via lymphatic stimulation from the needling
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Fine lines and crepiness, targeted through collagen stimulation
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Hydration and elasticity, restored through polynucleotide activity in the dermis
What to Expect on the Day
The treatment takes around 60 minutes from start to finish. Numbing cream is applied beforehand, so discomfort during the procedure is minimal for most people.
After the session, you may experience mild redness and some slight swelling, particularly in the under-eye area. This typically settles within a few hours. Most clients return to normal activity the same day or the following morning.
Results begin to show within a few weeks as the skin heals and collagen remodelling progresses. The full benefit builds over several weeks, with many clients noticing continued improvement for up to three months after treatment.
Book a Consultation at Injectual London
If you want to understand whether microneedling and polynucleotides are right for your specific concerns, start with a consultation. The team will assess your skin, explain what results are realistic, and build a plan around your goals. Book a consultation today.