Hair Thinning in Women: Can Polynucleotides and CALECIM® Help?

Posted by Michal Krupien on

Hair thinning is one of the most common concerns among women today and yet, it’s often brushed aside or misunderstood. If you're noticing reduced density, more shedding in the shower, or a general loss of volume, you're not alone. The good news is that new, regenerative treatments are offering real hope without surgery or harsh medications.

At Injectual London, we specialise in two of the most advanced non-surgical solutions: polynucleotide therapy and the CALECIM® Advanced Hair System. When used individually or in combination, these treatments can help restore fuller, healthier hair naturally and effectively.

Understanding Female Hair Thinning

Women experience hair loss differently from men. Instead of full bald patches, it often presents as diffuse thinning across the crown, widening of the parting, or overall volume loss. This can be due to:

  • Hormonal changes (e.g. menopause, postpartum)

  • Chronic stress

  • Nutritional deficiencies

  • Inflammation or scalp conditions

  • Genetics and ageing

Rather than masking the issue, the goal is to target the root causes — and that’s where regenerative medicine steps in.

Polynucleotides: A Regenerative Approach to Hair Growth

Polynucleotides are bio-molecules derived from DNA that support cell repair and tissue regeneration. When injected into the scalp, they work by:

  • Stimulating dormant hair follicles

  • Improving blood flow to the scalp

  • Extending the hair growth phase

  • Enhancing scalp health and reducing inflammation

Unlike topical solutions or synthetic medications, polynucleotide injections work with your body to reactivate natural hair growth. The results look and feel like your own hair — because they are.

Women experiencing early-to-moderate thinning, postpartum shedding, or general volume loss often respond well to this treatment. A typical protocol involves three sessions over a few months, with visible thickening and regrowth emerging within 6 to 12 weeks.

CALECIM® Advanced Hair System: Stem Cell-Driven Results

For those seeking a clinically proven boost in hair density, CALECIM® offers a powerful solution. Backed by lab research, this six-week programme uses stem cell-derived proteins from umbilical cord lining extract to:

  • Stimulate follicle cell growth (by up to 24%)

  • Reduce scalp inflammation

  • Strengthen fragile hair strands

  • Minimise shedding and breakage

  • Promote long-term follicular repair

The key ingredient is PTT-6®, a unique complex of over 3,000 regenerative proteins including exosomes, growth factors, and cytokines. Whether used at home with derma stamping or administered in-clinic by Injectual’s specialists, CALECIM® delivers visible improvements in volume, texture, and scalp health.

The Power Combo: Polynucleotides + CALECIM® 

At Injectual, we take things further. By combining polynucleotide injections with CALECIM® at select appointments, we supercharge your results. While CALECIM® provides the building blocks for follicle growth, polynucleotides create the perfect environment for that growth to thrive improving circulation, reducing inflammation, and supporting scalp regeneration.

This enhanced protocol is ideal for women looking to achieve the most dramatic yet natural results without surgery.

Why Choose Injectual?

Injectual is one of London’s leading aesthetic clinics for regenerative treatments. When it comes to hair restoration, we offer:

  • Personalised treatment plans for women at all stages of hair loss

  • Expert-led protocols using the latest technology

  • Combination approaches for maximised results

  • Discreet, comfortable clinics in Shoreditch and Notting Hill

Whether you’re just noticing hair thinning or have been struggling with it for years, our team is here to guide you with compassion and expertise.

Is This Treatment Right for You?

You may be a good candidate if you’re experiencing:

  • General thinning or reduced hair volume

  • Receding hairline or patchy areas

  • Postpartum or menopause-related shedding

  • Weak, brittle hair prone to breakage

  • No underlying medical condition affecting hair follicles

If that sounds like you, we encourage you to book a consultation to find the right path forward.

Take the First Step Toward Healthier Hair

Hair thinning can impact your confidence  but it doesn’t have to be permanent. With Injectual’s advanced treatments like polynucleotide therapy and the CALECIM® Advanced Hair System, you have powerful, non-invasive options to support regrowth and restore your natural hair density.  Book your hair restoration consultation today at Injectual London.

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