Microneedling + Fillers + Polynucleotides: The Power of Treatment Stacking

Posted by Michal Krupien on

Gone are the days of one-size-fits-all treatments. In 2025, the most impressive results come from stacking—strategically combining complementary treatments that target multiple skin concerns at once.

At Injectual, one of our most effective combinations is: Microneedling + Polynucleotides + (Optional) Dermal Fillers.

This non-surgical power trio enhances skin quality, structure, and cellular health all in a single protocol.

Let’s break down why this works.

What Is Under Eye Microneedling + Polynucleotides?

This is one of our most in-demand combinations, particularly for the delicate under-eye area.

  • Microneedling uses ultra-fine needles to create micro-injuries in the skin, triggering your body’s natural healing response and boosting collagen.

  • Polynucleotides (PNs) natural DNA fragments, often from salmon sperm supercharge that healing by stimulating cell repair, hydration, and regeneration.

Together, they address the root causes of common under-eye concerns with precision and minimal downtime.

Benefits of Microneedling + Polynucleotides

Improved Skin Regeneration

Microneedling kickstarts tissue repair. Polynucleotides enhance it at the cellular level—reducing wrinkles, boosting radiance, and smoothing texture faster than either treatment alone.

Boosted Hydration + Elasticity

PNs help your skin retain moisture, making them ideal for thin, dry, or crepey under-eye skin. The result? Firmer, plumper, healthier skin over time.

Reduction in Bags + Puffiness

Microneedling improves lymphatic drainage, which helps reduce under-eye bags. PNs assist with vascular repair, improving tone and reducing puffiness.

Brighter Eyes, Less Fatigue

This combo targets dark circles by improving blood flow and pigmentation from the inside out—not just masking it on the surface.

Why Add Dermal Fillers?

While microneedling and PNs improve skin quality, fillers enhance structure. For clients with:

  • Volume loss under the eyes

  • Hollow tear troughs

  • Mid-face deflation

Are You a Good Candidate?

You might benefit from Under Eye Microneedling + Polynucleotides if you:

  • Have dark circles, puffiness, or fine lines

  • Experience dryness or sagging under the eyes

  • Want to prevent deeper ageing signs

  • Prefer natural, needle-based skin regeneration

  • Want minimal downtime with long-lasting results

Filler may be added if you also show volume loss or hollowing.

Book the Best Under Eye Microneedling + Polynucleotides in London

At Injectual, we combine medical precision with artistic expertise. Our Under Eye Microneedling + Polynucleotide treatment is performed by skilled practitioners using only the most advanced techniques and materials.

Ready to experience the power of stacking? Book your complimentary consultation today. 

FAQs

What is this treatment exactly?

It combines microneedling and polynucleotide application to stimulate collagen and repair under-eye skin.

Is it painful?

Most clients report minimal discomfort. We use a topical anaesthetic for comfort.

When will I see results?

You’ll start noticing changes in 2–3 weeks as the skin regenerates. Improvements continue over months.

Can I combine this with other treatments?
 

Yes. We often combine it with under-eye filler or skin boosters for enhanced results.

Is there downtime?

Minimal. You might experience slight redness or swelling for a few hours post-treatment.

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