If your under-eye area is starting to show signs of fatigue, fine lines, or dark circles, you're not alone. The skin here is thinner and more delicate than anywhere else on the face, making it one of the first places to show ageing and stress. That’s why at Injectual, London’s leading aesthetics clinic, we offer an advanced solution that combines two powerful treatments in one: microneedling with polynucleotides.
This pairing goes far beyond a standard facial. It’s a regenerative skin therapy that works on a cellular level to restore strength, brightness, and elasticity in one of the most sensitive areas of the face.
What Makes This Combination So Effective?
Microneedling creates micro-channels in the skin that stimulate your body’s natural healing response. On its own, it encourages collagen production and enhances texture. But when you introduce polynucleotides during the same session, the results are significantly amplified.
Polynucleotides are naturally derived molecules that repair damaged skin, promote cellular turnover, and attract hydration to the treated area. When applied to the freshly microneedled skin, they absorb deeply and begin to work immediately. The combination helps target a wide range of concerns including:
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Fine lines and crepey texture
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Under-eye bags and puffiness
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Dark circles and dullness
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Loss of elasticity and hydration
This is not a filler, nor is it a harsh resurfacing procedure. It’s regenerative care designed to restore your skin from within.
Enhance Your Results with CALECIM® Exosomes
For those looking to supercharge their microneedling treatment, we also offer CALECIM® exosomes as a powerful add-on.
Derived from ethically sourced umbilical cord lining stem cells, CALECIM® exosomes are rich in growth factors, peptides, and proteins that accelerate skin regeneration. When applied after microneedling, they help:
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Speed up healing and reduce redness
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Enhance collagen production and firmness
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Maximise cellular repair for faster, more radiant results
We use half the bottle in-clinic immediately after microneedling, and the remaining half is given to you to continue using at home—ensuring optimal recovery and extended benefits over the following days.
This optional upgrade is ideal for clients looking for faster downtime, improved skin texture, and a regenerative “boost” to their under-eye area.
What You Can Expect from Treatment
The treatment begins with a gentle cleanse and the application of a numbing cream to ensure comfort. Using ultra-fine needles, our practitioner performs microneedling specifically in the under-eye region. Once the micro-channels are created, a polynucleotide serum is applied and massaged into the skin, allowing for maximum absorption.
The entire procedure takes around 60 minutes. Most clients experience only mild redness immediately after, which typically fades within hours.
Visible Results, Minimal Downtime
You won’t need to take time off work or cancel plans. There is virtually no recovery period, making this treatment ideal for those who want visible change without disruption to their daily life.
Improvements appear gradually as your skin begins to heal and regenerate. Within a few weeks, you’ll notice:
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Brighter, more even skin tone under the eyes
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Firmer and smoother texture
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A reduction in fine lines and visible puffiness
For long-term results, we typically recommend a course of 3 to 6 treatments, spaced a few weeks apart.
Is It Right for You?
This treatment is suitable for all skin types and is especially helpful for those who:
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Want to avoid dermal fillers
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Have early signs of ageing
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Struggle with chronic puffiness or dark circles
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Experience under-eye volume loss but prefer a more natural approach
During your consultation, we’ll assess your concerns and tailor a plan to your needs. Many clients also choose to combine this treatment with our Injectual Polynucleotide Cocktail or Salmon Sperm Facial for full-face rejuvenation.
A Smarter Approach to Skin Rejuvenation
What sets microneedling with polynucleotides apart from other treatments is how deeply it supports the skin’s biology. Rather than just masking concerns, this treatment restores the skin’s structure and function. You’ll not only look more refreshed, but your skin will actually be healthier.
If you’ve tried creams and serums with little success, or you’re not ready for injectables, this is a proven middle ground backed by science and trusted by our London clients.
Book Your Consultation at Injectual
Injectual is proud to be at the forefront of regenerative skin care in London. Our expert practitioners use the latest techniques and research-led products to help you achieve the best results with the least disruption. Book your consultation today and experience the benefits of microneedling with polynucleotides for yourself.
