Polynucleotide microneedling is becoming one of the most in-demand treatments for those seeking visible, non-surgical skin rejuvenation. At Injectual, we’ve seen firsthand how this treatment transforms tired, dull skin into something noticeably brighter, smoother, and firmer — particularly in delicate areas like under the eyes.
This post will walk you through what polynucleotide microneedling actually does and what kind of results you can realistically expect from your sessions.
What Is Polynucleotide Microneedling?
The treatment combines two powerful elements. Microneedling stimulates your skin’s natural healing process by creating thousands of micro-channels across the surface. Polynucleotides — molecules derived from DNA — are then introduced to support regeneration, reduce inflammation, and promote tissue repair.
Together, they create a potent response in the skin. Over time, clients often notice improvements in texture, hydration, tone, and elasticity.
What Results Can You Expect?
While individual results vary, here’s what many people experience after a course of treatments:
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Brighter and more even skin tone
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Smoother texture, especially around the eyes
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Less visible fine lines and creases
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Improved firmness and hydration
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Reduced puffiness and dark circles
These results don’t happen overnight. Polynucleotide microneedling works progressively, which means the most noticeable changes typically appear a few weeks after your session. For long-term improvements, a series of treatments is usually recommended.
Before and After Treatment: What You’ll Notice
Immediately after treatment, your skin may look slightly flushed — this is completely normal and fades quickly. Within a few days, most clients say their skin feels smoother and looks more radiant.
After multiple sessions, deeper changes begin to show. Collagen production increases, polynucleotides continue to support cell regeneration, and the overall skin structure becomes healthier and more resilient.
Ready to Start Your Skin Transformation?
If you're curious about how polynucleotide microneedling could work for you, the best next step is a consultation. At Injectual, we’ll assess your skin and tailor the treatment to your goals.
Visible results. Minimal downtime. Expert-led care in the heart of London.