Polynucleotides vs. Tear Trough Filler: What’s Best for Under-Eye Rejuvenation?

Posted by Michal Krupien on

If you’re tired of looking tired, under-eye treatments promise a brighter, younger appearance. But not all solutions work the same way. Two of the most popular options in London are polynucleotide under-eye rejuvenation and tear trough fillers. Both address similar issues like dark circles, hollows, and fine lines  but they work differently and suit different people.

So which is better for you? Here’s a breakdown.

What Are Polynucleotides?

Polynucleotides are regenerative molecules naturally found in the body. When injected into the skin, they trigger a healing response. That includes:

  • Stimulating collagen production

  • Improving hydration and elasticity

  • Repairing damaged tissue

At Injectual London, our polynucleotide treatments specifically target the under-eye area, helping to reduce:

  • Dark circles

  • Fine lines

  • Puffiness

  • Hollowness

These are not volume fillers. They don’t change your face. They improve the quality of your skin.

What Are Tear Trough Fillers?

Tear trough fillers are hyaluronic acid-based injectables that add volume beneath the eyes. They're used to:

  • Fill hollows

  • Disguise under-eye bags

  • Smooth the transition between the lower eyelid and cheek

The result is instant — a fresher, more rested look after just one session. This treatment is widely available and has been a staple in under-eye rejuvenation for over a decade.

Key Differences Between Polynucleotides and Tear Trough Filler

1. Goal of Treatment

  • Polynucleotides repair and regenerate skin over time. They don’t fill but rebuild.

  • Tear trough fillers instantly replace lost volume.

2. Results Timeline

  • Polynucleotides take a few weeks to show results and often require a series of sessions.

  • Tear trough fillers offer immediate changes, typically visible the same day.

3. Natural Appearance

  • Polynucleotides support your skin’s natural structure. The result is subtle and progressive.

  • Tear trough filler can be natural too, but there's a higher risk of puffiness or overfilling if not done precisely.

4. Suitability

  • Polynucleotides work best for those with dark circles, fine lines, or mild hollowness.

  • Tear trough filler is ideal for those with under-eye volume loss — not heavy bags.

5. Risk Profile

  • Polynucleotides have a lower risk of complications.

  • Fillers can cause swelling, Tyndall effect (a bluish tint), or irregularities if poorly placed.

Injectual's Approach to Polynucleotide Treatments

Injectual offers one of London’s most advanced under-eye treatments using polynucleotides. Each session is handled by skilled practitioners who may also combine treatments with micro-needling or Injectual’s Polynucleotide Cocktail, which includes:

  • Polynucleotides

  • Jalupro

  • NCTF 135

This multi-layered approach improves texture, hydration, and elasticity all at once. No volume is artificially added — just better, brighter skin.

What’s the Best Option for You?

Choose Polynucleotides If:

  • You want natural improvement over time

  • Your main concern is skin quality, not volume

  • You’ve had fillers before and didn’t like the look

  • You prefer lower-risk, regenerative treatments

Choose Tear Trough Filler If:

  • You want fast results

  • You have visible hollows without much puffiness

  • You’re happy with subtle volume changes and know you’re a good candidate

Who Should Avoid Tear Trough Fillers?

You are not a good candidate for tear trough filler if you:

  • Have prominent eye bags (filler can worsen puffiness)

  • Tend to swell easily or have malar edema

  • Want skin improvement without volume changes

In these cases, polynucleotides are safer and more effective.

The Verdict: Repair vs Replace

Polynucleotides repair. Fillers replace. The best choice comes down to your skin condition, your tolerance for downtime, and your expectations.

For many, polynucleotides offer a more natural, regenerative route with fewer risks and longer-term benefits. For others, filler is the quick fix.

Book Your Consultation in London

Still unsure? Book a consultation at Injectual in Shoreditch or Notting Hill. Our team will assess your under-eye area and recommend the right option for your anatomy and goals.

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