Polynucleotide Treatment for Skin

Polynucleotide Treatment for Skin

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With age, the gradual decline of collagen and elastin reveals itself through dryness, uneven texture, lines and lacklustre tone. If your skin has lost its youthful bounce, polynucleotide injections for skin provide an innovative solution for naturally plumping and smoothing your complexion from within.

How Do Polynucleotides Renew Your Skin?

During minimally invasive treatment, these nucleotide complexes are administered via multiple microinjections into the skin's deeper dermis. Here, polynucleotides (PNs) begin signalling fibroblasts to generate new collagen and elastin fibres that restore firmness and support. Clinical studies show polynucleotides also assist in melanin suppression and hydration levels for an even, glowing appearance. Within 4-6 weeks of treatments, subtle yet significant improvements emerge as the skin rebuilds itself from a place of renewed fullness, clarity and radiance.

Key Benefits of Polynucleotides Treatment for Skin

  • Plumper Complexion: Stimulated collagen restores elasticity and fullness for dewier-looking skin.
  • Even, Luminous Tone: Studies show PNs may reduce hyperpigmentation and freshen tired complexions over time.
  • Softened Ageing Signs: Improved scaffolding and hydration minimise the look of lines and wrinkles.
  • Smooth Texture: Enhanced cell turnover helps refine pores and may fade acne scarring for an airbrushed effect.
  • Protection: A reinforced moisture barrier and connective tissues defend against further environmental damage.
  • Minimal Disruption: Most experience only minor tenderness, allowing an immediate return to normal routine.

Are You a Suitable Candidate for Polynucleotides Treatment for Skin?

Polynucleotides revitalise dull, ageing skin in a safe, gradual manner ideal for most adult complexions. Indicators you may benefit include:

  • Loss of firmness, lines or wrinkles due to intrinsic or environmental factors
  • Dryness, flakiness or signs of dehydration
  • Uneven texture, enlarged pores or acne scarring
  • Sun damage like age spots, freckles or melasma patches
  • Desire to offset future photoaging or maintain skin health
  • Wishing to glow with sheer, hydrated coverage instead of makeup

Compare Polynucleotides Skin Treatment to Other Skin Solutions




Maintenance Needed

Polynucleotides Skin Injections

Minimal (1-3 days)

Gradual tightening and glow over 6-12 months

Annual touch-ups


1-5 days

Temporary plumping; smoothing within 3 months

Every 4-6 months

Chemical Peels

5-10 days

Refinement in 3-6 months

Repeat every 3-6 months

Laser Resurfacing

5-14 days

Visible lifting in 3 months

Regular treatments to maintain

Facial Surgery

1-2 weeks

Dramatic contouring; non-gradual

Longevity but risks of surgery

As you can see, polynucleotide injections for skin smoothly renew skin in a gradual, natural manner offering the best risk-to-benefit ratio.

Book The Best Polynucleotides Treatment for Skin in London

Schedule your polynucleotide for skin consultation to restore firmness, clarity and glow to your complexion. Our experts will assess your unique concerns before customising an optimised treatment plan. Bid farewell to dry, dull skin and reclaim vibrant radiance - book now to start your polynucleotide journey towards a rejuvenated you!

Frequently Asked Questions

Gradual improvements emerge within 4 weeks as collagen stimulates over 3-6 months.

With annual touch-ups, benefits may persist long-term. Without maintenance, effects gradually soften over 12-18 months.

Most report minimal pinpricks but no pain. Any tenderness fades within hours.

Yes, the treatment safely enhances all adult skin in need of renewal.

For precaution, we don't recommend polynucleotides during pregnancy or nursing until more research is available.

A series of 3-6 sessions spaced 4 weeks apart often yields superb skin rejuvenation.

Yes, over time, stimulated collagen helps reduce the appearance of scars for smoother texture.


5 Star reviews

Treatment by leading medics only

Plastic Surgeon founded

Complimentary consultation available


We just know you'll love your treatment with us so we're giving you £100 off your 1st treatment (over £300). Book your complimentary consultation below to start your aesthetic journey.



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Our Injectual Practitioners

Founder Plastic Surgeon Dr. Veerle

Our founder Dr. Veerle, MD, FEBOPRAS, FCCP, is one of London's leading female plastic surgeons and is the co-founder of London’s holistic clinic, Tempus Belgravia. As her favourite motto is 'To be the best you need to learn from the best', Dr. Rotsaert has been travelling the world on the hunt for the world's leading techniques. Her and her peers' knowledge and skill have been used to create 5 proprietary techniques that will be used in all INJECTUAL clinics and by all injectors.

As founder of Injectual, Dr Rotsaert’s knowledge and understanding of both the surgical and non-surgical landscape is invaluable, and her commitment to helping enhance her patients’ lives continues to inspire.

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Aesthetic Doctor Thivos

Dr Thivos is a qualified doctor with a strong passion in aesthetic medicine. He graduated from one of the most prestigious medical schools in the world - Imperial College London. As well as his specialism in facial aesthetics, he has a background of working in medicine, surgery, psychiatry and A&E and has a strong background of anatomy and physiology.

Dr Thivos takes a holistic approach for bespoke treatment planning with his patients, aiming to enhance their features and bring beautiful results while maintaining natural and harmonised outcomes.

Specialties: Under Eye + Noses + Facial Feminisation/Masculinisation

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Aesthetic Nurse Shantel

Shantel Noble is an Independent Nurse Prescriber (INP) and clinical trainer. Shantel has been working full time in aesthetics since finishing a masters qualification (level 7) in non-surgical aesthetic medicine in 2018. After finalising her Level 7, she decided to combine her passion for skin with teaching and become an aesthetics trainer for Harley Academy.

Shantel’s ethos is about achieving natural results, beautifying and restoring what was once had without changing your unique qualities.

Shantel prioritises patient safety, ethical practice and ensuring each person has a comfortable experience.

Specialties: Artistic Transformation + Profhilo + Skincare

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Dr Janine is an Aesthetic Doctor who graduated with a Bachelor of Dental Surgery from the University of Bristol in 2017 and has a Master’s qualification (the highest qualification for injectables) in non-surgical facial aesthetics. With a passion for teaching, Dr Janine thrives as a clinical trainer at the renowned Harley Academy.

Dr Janine is committed to maintaining facial balance and harmony, whilst creating a bespoke treatment plan. She also takes pride in treating patients holistically, thereby ensuring natural results that are both beautiful and elegant.

Specialties: Mid- and lowerface rejuvenation + Anti-wrinkle treatments

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aesthetic doctor nadia

Dr Nadia Taha, is a practicing GP, a General Medical Council registered Doctor and a Harley Academy trained Aesthetic Doctor. Having earned her medical degree from the University of Birmingham Medical School with a background in Plastic and Reconstructive Surgery, she believes in delivering excellence with her expertise in a safe and comfortable environment.

Dr Taha is passionate about helping clients and therefore, offers cutting-edge safe innovations and the best non-surgical treatments to achieve natural looking but profound results.

Specialities: Cheek, Nasolabial & Temple filler

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Dr. Goziem - Aesthetic Doctor

Introducing Dr. Goziem Onuchukwu a highly experienced facial aesthetic practitioner known for her natural and stunning results. With prestigious academic qualifications from Barts and London, and a Masters in Aesthetic Medicine from Queen Mary's University of London, she brings a keen eye for detail and facial harmony. 

Dr. Goziem's approach emphasises the latest techniques and personalised care to address various skin concerns. Her warm and friendly demeanour ensures a comfortable experience for every client, while her commitment to safety and evidence-based treatments guarantees excellent results.

Specialities: Skin + Anti-wrinkle treatment 


Shima - Aesthetic Pharmacist

Shima Samivand is an Independent Pharmacist Prescriber (PIP) and a fully qualified Aesthetic Practitioner. Shima is particularly passionate about skin health and an advocate for medical-grade skincare.

Shima prides herself in providing personable advice supported by safe and evidence-based treatments and is a strong believer that subtle enhancements offer the best results. Having trained under some of the UK’s most respected aesthetic professionals, Shima combines the latest treatment methods with her patient centred approach to achieve her favourite aspect of the job - witnessing the confidence boost that non-surgical treatments offer to patients!

Specialties: Skin, lip enhancements and anti-wrinkle treatments

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We just know you'll love your treatment with us so we're giving you £100 off your 1st treatment (over £300). Book your complimentary consultation below to start your aesthetic journey.

Where are we located? 

Our lovely Westbourne Grove studio is easily reachable by public transport from most central London locations and is located in the heart of the iconic Notting Hill. Most of our clients come from nearby neighbourhoods: Paddington, Hyde Park, Green Park, Bayswater, Soho, Kings Road, South Kensington, Kensington, Chelsea, Battersea, Fulham, Regents Park, Primrose Hill, St Johns Wood, Victoria, Mayfair, Knightsbridge, Belgravia, Fitzrovia, Holland Park, Earls Court, Highgate, West Brompton, Westminster, Islington, Hampstead, Hammersmith, Battersea or Nine Elms



TEL: +44 2039 519 115

Mon - Saturdays: 10am - 6pm