GET £100 OFF YOUR 1ST TREATMENT

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FLEXIBLE FINANCING AVAILABLE

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GET £100 OFF YOUR 1ST TREATMENT

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FLEXIBLE FINANCING AVAILABLE

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Plinest Polynucleotides
Plinest Polynucleotides
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 5.0
Based on 2000+ customers

Plinest Polynucleotides

£350.00
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The Future of Injectables

Are you looking for a solution to tired-looking eyes, dull skin, or stubborn wrinkles? At Injectual, we offer Plinest Polynucleotide treatments, a revolutionary approach to skin and hair rejuvenation in London. From minimising under-eye puffiness to smoothing fine lines and improving skin elasticity, Plinest treatments work at a cellular level to restore your youthful glow. What make Plinest the preferred brand at Injectual is their trademarked technology named HPT (Highly Purified Technology), which means they are the most purified polynucleotides on the market.

Discover how this innovative treatment can transform your appearance and help you regain confidence in your skin.

What are Plinest Polynucleotides?

Plinest polynucleotides are the ultimate breakthrough in regenerative aesthetics. Derived from DNA’s building blocks, polynucleotides work by repairing and rejuvenating skin cells. Unlike traditional treatments that target surface-level concerns, Plinest stimulates your skin’s natural repair mechanisms, promoting collagen and elastin production to enhance skin structure and elasticity.

Plinest is a versatile treatment suitable for addressing under-eye concerns, acne scars, hyperpigmentation, and even thinning hair, offering a comprehensive solution for those seeking a natural yet effective approach to rejuvenation.

How Do Plinest Polynucleotides Work?

Plinest treatments utilise carefully administered micro-injections to deliver polynucleotides into the skin. These polynucleotide chains:

  • Stimulate fibroblasts, which produce collagen and elastin, restoring skin’s shape and volume.

  • Improve microcirculation, reducing puffiness and dark circles under the eyes.

  • Enhance hydration by boosting the extracellular matrix of skin cells.

  • Protect against free radicals, inflammation, and environmental damage, improving overall skin health.

Am I Suitable for Plinest Polynucleotides?

Plinest Polynucleotide treatments are suitable for most people seeking a non-surgical solution for skin rejuvenation. It is particularly effective for:

  • Individuals experiencing fine lines, wrinkles, or sagging skin.

  • Those with dehydrated or dull skin.

  • Clients suffering from dark circles or puffiness under the eyes.

  • People with rosacea, hyperpigmentation, or acne scars.

  • Anyone looking to improve overall skin health and elasticity.

During your consultation at Injectual, our clinicians will assess your skin and discuss your goals to ensure this treatment is the right fit for you.

Comparison Table: Plinest vs Other Treatments

Feature

Plinest Polynucleotides

Dermal Fillers

Profhilo

Mechanism

Repairs DNA, boosts collagen/elastin

Adds volume to specific areas

Boosts hydration and firmness

Results Onset

Gradual, within 3 months

Immediate

Gradual, 2-3 weeks

Duration of Results

6+ months

6-12 months

6 months

Side Effects

Minimal bruising or swelling

Possible swelling/bruising

Minimal swelling

Areas Treated

Face, eyes, neck, hair, chest, etc.

Specific volume-deficient areas

Full face, neck, hands

 

Why Choose Plinest Polynucleotides Over Other Treatments?

Unlike traditional injectables like dermal fillers that provide instant but surface-level results, Plinest works deeper to repair and regenerate skin cells. While results take longer to appear, they are often longer-lasting and improve overall skin health.

By addressing underlying issues such as DNA repair and collagen production, Plinest offers a holistic solution that enhances your natural beauty and keeps your skin youthful and healthy.

In the Injectual Polynucleotide Cocktail, Plinest polynucleotides are combined with other leading rejuvenation ingredients like Jalupro and NCTF 135, creating a powerful, multi-targeted skin treatment. Here’s how Plinest is integrated and why the combination is so effective:

1. Plinest Polynucleotides with Highly Purified Technology (HPT)

Plinest polynucleotides, made using Highly Purified Technology (HPT), form the foundation of the Injectual Polynucleotide Cocktail. HPT ensures that the polynucleotides are of the highest purity and safety, allowing for more efficient tissue regeneration, collagen stimulation, and deep skin hydration. This purity makes Plinest particularly effective in restoring elasticity and repairing damaged skin.

2. Jalupro for Amino Acid Enrichment

Jalupro is added to the cocktail to provide an essential boost of hyaluronic acid and amino acids, which are critical for skin repair and collagen synthesis. Combined with Plinest polynucleotides, Jalupro enhances the skin’s ability to heal and renew itself, making the skin firmer, smoother, and more youthful.

3. NCTF 135 for Comprehensive Skin Nutrition

NCTF 135 is a mesotherapy solution rich in vitamins, minerals, and antioxidants. By incorporating NCTF 135 into the cocktail, Injectual ensures that skin cells receive the nutrients they need to function at their best. This works in harmony with the regenerative properties of Plinest, enhancing overall skin vitality and radiance.

4. Micro-Needling for Maximum Absorption

To amplify the effects of the Injectual Polynucleotide Cocktail, micro-needling is often used alongside the treatment. Microneedling creates tiny channels in the skin, allowing Plinest polynucleotides, along with Jalupro and NCTF 135, to penetrate deeper layers of the skin, resulting in faster and more profound rejuvenation.

5. Synergistic Benefits of the Combination

  • Plinest with HPT delivers high-purity polynucleotides that focus on cellular regeneration, hydration, and collagen production.

  • Jalupro accelerates skin repair with its amino acid content.

  • NCTF 135 nourishes and revitalises the skin with its comprehensive nutrient profile.

Together, this cocktail addresses multiple ageing concerns, such as wrinkles, loss of elasticity, uneven skin tone, and skin hydration. The result is long-lasting, natural rejuvenation, making it a top-tier treatment for clients looking for advanced skincare solutions.

The Injectual Polynucleotide Cocktail, featuring Plinest’s HPT technology, is ideal for clients seeking natural results with minimal downtime, and it positions Injectual as a leader in innovative, luxury skin treatments.

Book Your Plinest Polynucleotide Treatment in London Today

Ready to transform your skin? Discover the power of Plinest polynucleotides and enjoy long-lasting, natural results that revitalise your appearance.

Book Your Consultation Now and take the first step towards a more radiant, youthful you!

Most clients find the treatment comfortable, with only minor discomfort during the in


Treatment FAQ's

What is the downtime for Plinest treatments?

Downtime is minimal. You may experience mild swelling or bruising, but this typically resolves within 24-48 hours.

When will I see results?

Results develop gradually over 2-3 months as your skin regenerates and collagen production increases.

How long do the results last?

Results typically last 6 months, with many clients opting for maintenance treatments every 3-4 months.

Is Plinest suitable for sensitive skin?

Yes, Plinest is anti-inflammatory and designed to soothe sensitive skin while boosting its overall health.

Can I combine Plinest with other treatments?

Absolutely! Plinest works well alongside treatments like fillers or Profhilo to achieve comprehensive rejuvenation.

How many treatments do I need?

A typical course includes 3 sessions spaced 3-4 weeks apart, but this may vary based on individual needs.

Is Plinest painful?

Most clients find the treatment comfortable, with only minor discomfort during the injections.

Can Plinest treat areas other than the face?

Yes, Plinest can be used on the neck, chest, scalp, and other areas requiring rejuvenation.

Who is not suitable for Plinest?

Pregnant or breastfeeding individuals and those with certain medical conditions should consult their clinician before treatment.

What To Expect
Results develop gradually over 2-3 months as your skin regenerates and collagen production increases.
Downtime
Downtime is minimal. You may experience mild swelling or bruising, but this typically resolves within 24-48 hours.
Our Approach
Injectual is a doctor-led clinic specialising in regenerative, results-driven aesthetics. Every treatment is medically guided, bespoke, and designed to improve skin quality at a cellular level for natural, long-term results.
Treatment Areas
Where Can You Use Plinest Polynucleotides?

Face: Under the eyes, cheekbones, and jawline.

Neck and Décolletage: Tightens and rejuvenates sagging skin.

Hair: Improves hair density and scalp health.

Lips and Eyebrows: Enhances skin texture and appearance in delicate areas.

Body: Inner arms and thighs for firmer, hydrated skin.


Designed for results you can see and feel

We aim to standardise, democratise and modernise medical aesthetics, ensuring the highest level of expertise, integrity and safety.

Key Features and Benefits

Highlights and Core Advantages
What It Targets?

Injectual Practitioners

Your safety is our priority. At Injectual, you will only ever be treated by highly qualified medical professionals, including Surgeons, Doctors, and Specialist Nurses.
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DR VEERLE ROTSAERT

Dr. Veerle Rotsaert, MD, FEBOPRAS, FCCP, is one of London’s most accomplished female plastic surgeons and a leading authority in advanced injectables. As co-founder of Tempus Belgravia and Injectual, she is renowned for her dual mastery in complex surgical procedures and cutting-edge non-surgical techniques, a rare combination that ensures her patients achieve harmonious, natural results.

Guided by her philosophy “To be the best, you need to learn from the best”, Dr. Rotsaert has trained under the most celebrated surgeons and aesthetic experts worldwide. Her global expertise has contributed to the creation of five proprietary injectable techniques, now used across all Injectual clinics and forming the gold standard for the brand’s protocols.

A graduate of the University of Leuven in Belgium, Dr. Rotsaert completed Plastic, Aesthetic and Reconstructive Surgery training at leading institutions around the world. She is a Fellow of the European Board of Plastic Surgeons, a Fellow of the College of Chest Physicians, and a member of both the British College of Aesthetic Medicine and the American Society of Plastic Surgery.

At Injectual, she plays a pivotal role in setting standards, training injectors, and innovating techniques that blend surgical precision with injectable artistry. Alongside treating patients, she develops skincare and treatment solutions designed to optimise and maintain results, supporting overall skin health.

Specialities: Complex facial and body surgery, surgical and non-surgical harmonisation, advanced injectable rejuvenation, and proprietary Injectual techniques.

Dr
Aesthetic Doctor Tony

Dr. Tony is a highly accomplished medical professional whose career blends academic excellence, clinical expertise, and a passion for education. A graduate of the University of Nottingham in Genetics and Biochemistry, he went on to complete his medical training at the University of Liverpool, graduating with merit.

With 8 years of experience in Surgical Specialties within the NHS and over 5 years in Aesthetic Medicine, Dr. Tony brings exceptional depth of medical knowledge and technical skill to every treatment. He is widely respected in the aesthetics industry, not only for his advanced clinical capabilities but also for his dedication to raising industry standards and innovating treatment approaches.

At Injectual, Dr. Tony is one of the principal training forces, playing a pivotal role in setting clinical protocols and quality benchmarks. His expertise ensures that every treatment performed under the Injectual name meets the highest standards of safety, efficacy, and ethics — reinforcing the clinic’s position as a leader in aesthetic medicine.

Alongside his work at Injectual, Dr. Tony is an Aesthetics Trainer for a large, nationally recognised training academy, where he teaches medical practitioners to become safe, confident, and highly skilled injectors. His approach blends scientific precision with artistic understanding, making him a sought-after mentor and thought leader in the field.

Internationally, Dr. Tony is recognised as an authority in masculinisation treatments and in the care of transgender and non-binary patients, delivering results that are affirming, empowering, and aligned with each individual’s goals. His work in this area is respected for its sensitivity, artistry, and deep anatomical expertise, helping patients feel seen, understood, and celebrated.

Dr. Tony offers a comprehensive range of treatments, from anti-wrinkle injections and dermal fillers to advanced injectable skincare (e.g., Profhilo, polynucleotides), microneedling, chemical peels, and holistic skincare consultations.

Specialities: Non-surgical nose jobs, skin boosters, masculinisation, transgender and non-binary patient care, and advanced skincare.

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Aesthetic Pharmacist Zain

Zain Ali, MPharm, is an internationally recognised force in the world of facial feminisation — a practitioner celebrated for his ability to combine scientific precision with aesthetic artistry. A dynamic pharmacist with a fresh and highly individualised approach to aesthetics, Zain seamlessly blends his deep pharmaceutical expertise with an unwavering passion for advanced skincare and injectable innovation.

After earning his Master’s degree in Pharmacy (MPharm) in 2018 and qualifying as an independent prescriber, Zain honed his expertise through years in luxury skincare before making his mark in aesthetics in 2021. His practice is defined by a meticulous understanding of facial anatomy, a refined artistic eye, and a commitment to enhancing natural beauty — particularly for women seeking elegant, harmonious feminisation.

Renowned for staying at the cutting edge of industry advancements, Zain specialises in botulinum toxinpolynucleotides (including the signature Injectual Polynucleotide Cocktail), skin boosters, and medical-grade skincare. His approach is grounded in evidence-based techniques and an innate sense of proportion, ensuring results that are both transformative and natural.

At Injectual, Zain is a key innovator and trendsetter, continuously elevating treatment standards and inspiring peers in the industry. Patients travel from far and wide for his expertise, knowing they are in the hands of a practitioner whose skill and precision have made him a respected name well beyond the UK.

Specialities: Facial feminisation, Injectual Polynucleotide Cocktail, skin boosters, anti-wrinkle treatments, and medical-grade skincare.

Dr
Aesthetic Doctor Nina 

Dr. Nina Cunning, MBChB, BSc (Med), is a distinguished aesthetic practitioner and skilled injector whose career seamlessly bridges advanced medical expertise with refined aesthetic artistry. She holds a Bachelor of Science in Medicine from The University of St Andrews and a Bachelor of Medicine and Bachelor of Surgery (MBChB) from The University of Glasgow — a foundation that underpins her meticulous, evidence-based approach to patient care.

With a background in Head and Neck Surgery, Dr. Cunning undertook prestigious specialist training followed by an intensive two-year fellowship in Robotic Head and Neck Surgery in London. This highly technical field demanded unparalleled anatomical knowledge, precision, and surgical dexterity — qualities that now define her aesthetic practice and set her apart as a practitioner of exceptional calibre.

Dr. Cunning is also deeply immersed in the global aesthetics community, regularly participating in international conferences and advanced training programmes. Her commitment to staying at the forefront of innovation ensures her patients benefit from the latest, safest, and most effective techniques available worldwide.

Known for her bespoke treatment planning, Dr. Cunning designs each aesthetic journey around the individual, marrying clinical skill with an intuitive understanding of beauty and proportion. Her warm, personable manner allows patients to feel at ease, while her artistry delivers results that are both transformative and natural.

Specialities: Advanced facial contouring, lip enhancements, polynucleotides, and The Injectual Polynucleotide Cocktail.

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Aesthetic Nurse Robyn

Nurse Robyn is a highly accomplished Aesthetic Nurse with over nine years of experience delivering an extensive range of aesthetic treatments. With a strong foundation in both clinical nursing and cosmetic procedures, she has developed a reputation for combining medical precision with an artist’s eye, consistently achieving results that enhance natural beauty while boosting her clients’ confidence.

Proficient in advanced injectable techniques — including anti-wrinkle treatments, dermal fillers, and skin boosters — as well as state-of-the-art skin rejuvenation therapies, Nurse Robyn approaches every treatment with meticulous attention to detail. Her ethos is built on listening deeply to each patient’s needs, engaging in thoughtful consultation, and creating bespoke treatment plans that reflect their unique features and aspirations.

Renowned for her delicate touch and ability to deliver subtle yet impactful transformations, Nurse Robyn is particularly sought after for her work in under-eye enhancement and lip augmentation. Her compassionate, personable manner ensures that every patient feels comfortable, informed, and confident in their treatment journey.

Specialities: Under-eye enhancement, lip filler, advanced injectables, and skin boosters.

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Aesthetic Nurse Lydia

Nurse Lydia is a highly skilled Registered Nurse Prescriber and accomplished aesthetic practitioner at Injectual, renowned for her ability to deliver regenerative, skin-transforming treatments that are as subtle as they are powerful. With a deep passion for skin health and an artistic approach to aesthetic medicine, Lydia guides her patients through transformative skin journeys that elevate natural beauty and restore youthful radiance.

Holding a prestigious Level 7 Diploma in Clinical Aesthetic Injectable Therapies, Lydia has trained under internationally recognised consultant plastic surgeons, ensuring every patient benefits from the highest standards of safety, precision, and artistry. Her expertise spans polynucleotides (including advanced under-eye rejuvenation), exosome therapymicroneedlinglip enhancement, and anti-wrinkle treatments — allowing her to design comprehensive, multi-modal plans that address both immediate concerns and long-term skin vitality.

Lydia is particularly admired for her knowledge and flair in skin regeneration, using cutting-edge innovations such as exosomes to stimulate repair, improve texture, and promote a luminous, healthy complexion. Her patients value not only her technical skill but also her compassionate, consultative approach, ensuring they feel informed, comfortable, and confident throughout their treatment journey.

Specialities: (Under-eye) polynucleotides, exosome therapy, microneedling, artistic transformations, lip enhancement, anti-wrinkle treatments, and advanced skin rejuvenation.

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Dr. Fiori Teklebrhan

Dr. Fiori Teklebrhan, MBBS, BSc (Hons), Dist. Aesthetic Medicine, is an exceptionally skilled aesthetic doctor and one of Injectual’s most experienced injectors, renowned for her meticulous technique, artistic precision, and dedication to natural yet impactful results. Holding a First-Class Honours BSc in Psychology, a Bachelor of Medicine and Bachelor of Surgery (MBBS), and a Distinction in Aesthetic Medicine from Queen Mary University of London, she brings a rare combination of medical excellence, psychological insight, and aesthetic artistry to her work.

Since specialising full-time in aesthetics in 2022, Dr. Fiori has already performed over 1,500 injectable treatments, earning a reputation as a trusted expert for patients seeking elegant, balanced transformations. Her advanced skill set spans toxin, dermal fillers, Sculptra, skin boosters, and polynucleotides, enabling her to address both structural enhancement and regenerative skin health with equal expertise.

With a background in breast surgery and anatomy teaching, Dr. Fiori’s deep understanding of facial structure and proportion allows her to deliver treatments that are not only beautiful but anatomically precise. She is particularly renowned for midface and lower face sculpting, where her work restores youthful contours while maintaining the patient’s natural individuality.

Her commitment to ethical, patient-centred care ensures that each treatment plan is bespoke, aligning with the patient’s goals and focusing on subtle enhancement, longevity, and skin vitality. Passionate about regenerative treatments, Dr. Fiori champions innovative approaches — from Sculptra to polynucleotides — to achieve radiant, healthy skin and lasting confidence.

Specialities: Midface and lower face sculpting with dermal fillers, volumisation and collagen stimulation with Sculptra, skin brightening with polynucleotides and skin boosters, and advanced toxin treatments.

Real Results from Our Community

Injectual Testimonials
Frey
Treatment
Insta-Injectual Facial, Polynucleotides eye, 3 areas of toxin
Review

Injectual is my absolute go-to for a total skin transformation; the combination of microneedling, a PRX peel, and targeted toxins perfectly balanced my features. Adding polynucleotides under the eyes was a game-changer for a refreshed look. I couldn't be happier with these professional, medical-led results

Book Your Treatment

Begin your transformation today.

Book Now
Jack Nuzum
Treatment
Polynucleotides and Exosomes
Review

The medical team at Injectual completely transformed my skin prep with a strategic protocol of exosomes and polynucleotides. My complexion has never looked clearer or more luminous—it's the ultimate cellular-level glow that left me feeling perfectly rested and camera-ready for my event!

Book Your Treatment

Begin your transformation today.

Book Now
Shakeel Murtaza
Treatment
Polynucleotides Eye
Review

I've been struggling with stubborn dark circles for a while, so I visited INJECTUAL for a Salmon DNA skin boost. The Polynucleotides treatment was a total game-changer for my under-eyes. Just look at my before and after

Book Your Treatment

Begin your transformation today.

Book Now
Amy Hancock
Treatment
Jalupro and Lip Flip
Review

The professional, medical-led team in Notting Hill made me feel completely at ease for my holiday glow-up. After the Jalupro Super Hydro treatment, my skin feels incredibly hydrated and firm, with a radiant, youthful dewiness that is perfect for the season!

Book Your Treatment

Begin your transformation today.

Book Now
Gabz Tooma
Treatment
Anti-Wrinkle and Lip Flip
Review

I am so impressed with Dr. Nina's expertise; she achieved a perfectly natural look that smoothed my skin without any 'frozen' feel. The subtle lip flip gave me that extra boost of confidence I was looking for, proving that a little tweak really does make all the difference!

Book Your Treatment

Begin your transformation today.

Book Now
Eva
Treatment
Polynucleotides and Lip Filler
Review

Zain is a true professional; the combination of Polynucleotides and lip filler left my skin looking revitalised and my lips perfectly defined. The results are incredibly natural and have given me a refreshed, glowing look that I absolutely love

Book Your Treatment

Begin your transformation today.

Book Now
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Not sure which treatment is right for you?

Book your free consultation with our expert specialists and create a personalised plan to achieve your goals

The Injectual Experience

Book complimentary consultation

Receive £100 off your first treatment over £300 with code DRV100. Personalised treatments designed by medical experts for a naturally enhanced you.

Expertise You Can Trust

Led by renowned Plastic Surgeon Dr Veerle Rotsaert, our team of medical practitioners each have over five years’ experience in aesthetic medicine.

The Injectual Method

We use only the finest brands and our own techniques, developed by world leading aesthetic experts, to achieve subtle lasting results.

Natural Results Designed to Last

Injectables and skin treatments are like going to the gym for your skin. Regular visits help maintain, prevent and enhance.

£

Accessible Aesthetics

Enjoy premium injectables through yearly packages, flexible payment plans and memberships tailored to your needs.

Recovery & Beyond

Every client receives a complimentary 15 minute LED therapy session. Our Injectual Skincare range supports long term skin health.

Book Your Consultation

Start your journey with a complimentary consultation and discover the Injectual difference.

FAQ's

Your questions, answered. Can’t find what you’re looking for? Ask us below.

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What makes the INJECTUAL process so special?

We’re so glad you asked: even before you step into INJECTUAL we want to make sure you’re taken care of. Our customer service team is always available to answer any questions you may have and put you at ease. We like to think that INJECTUAL is more than just a clinic, it’s an immersive experience. From our state of the art waiting room, to our signature INJECTUAL techniques, to the highest trained professionals in the field, we want to make sure everything we do is to the highest standard. We offer the best in pain management techniques, including numbing cream and nitrous oxide. We also offer specialty in-studio aftercare (complimentary, of course) including a recovery room where you can relax for as long as you want with a LED light treatment that aids recovery and will leave your skin with an extra bit of glow. Come in and see for yourself what makes INJECTUAL special.

Do I need to avoid anything before the procedure?

Before your treatment, please avoid alcohol for 24h before the procedure, as this can thin the blood and increase the risk of bruising. Blood-thinners, like Ibuprofen, ginseng and Omega 3, should also be avoided. Make sure you DO have food and drink liquid on the day of your procedure to avoid light headedness.

Post treatment tips?

Try your best to not touch the treated area for 3 hours, avoid heavy lifting and intense physical exercise for at least 24 hours. Avoid excessive amounts of alcohol and sodium as this could lead to swelling. If you do experience some minor swelling, you can apply a cold compress for 15 minutes every hour. Paracetamol can help with any pain management. Be sure to sleep face up if you had a facial procedure. If you require any more assistance or help after your procedure, our expertly trained staff is always on hand to answer your questions and offer medical advice.

What are your opening times?

Clinic Hours: 
Monday: 10:00 – 18:00
Tuesday: 10:00 – 18:00
Wednesday: 10:00 – 20:00
Thursday: 10:00 – 18:00 (with extended hours until 20:00 on selected Thursdays — please enquire)
Friday: 10:00 – 20:00
Saturday: 10:00 – 18:00
Sunday: Closed

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'The Netflix of Injectables' - Join to spread the cost of your treatments, get exclusive discounts and many more benefits
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