Polynucleotides Treatment for Jowls

Polynucleotides Treatment for Jowls

Sale Save

With age, loose, wrinkled skin often develops beneath our cheeks and jaws, commonly known as jowls. While a natural part of the ageing process, sagging jowls can make you appear tired or sad. If you've been feeling self-conscious about loose facial skin dragging your appearance down, it may be time to try polynucleotides - a cutting-edge non-invasive solution for restoring definition and volume to your jawline.

How Polynucleotides Tighten Sagging Jowls

Polynucleotides (PNs) work their anti-aging magic by stimulating your skin's natural collagen and elastin production from within. During treatment, these nucleotide complexes are carefully injected into the layers of skin beneath the chin and jawline where they signal fibroblasts to start generating new collagen fibres. Within weeks, this restored support structure begins lifting and tightening hanging jowls for a sculpted facial profile. By encouraging long-term collagen synthesis, polynucleotides provide gradual yet significant tightening of loose skin over a course of 6 months

What are the Key Benefits of Polynucleotide Injections for Jowls?

  • Gradual yet significant tightening: By stimulating collagen production, PNs lift and contour loose facial skin over 6-12 months for a rejuvenated jawline.
  • Natural-looking results: Unlike invasive procedures, PNs yield subtle reshaping that maintains your distinctive facial features and identity.
  • Minimal downtime: Most patients experience little tenderness or side effects, allowing an immediate return to regular activities.
  • Optional volume restoration: For thinning faces, PNs can be combined with fillers to both tighten sagging skin and add fullness.
  • Prevention of further laxity: Annual maintenance helps lock in benefits and prevents recurring looseness long-term.
  • Improved facial definition: Refreshed jawline contours restore a slim, sculpted oval appearance for your lower face.
  • Improved jowl-neck contour: Loose neck skin is also lifted to complete facial rejuvenation along the entire jawline angle.

Who is a Suitable Candidate for Polynucleotides Treatment for Jowls?

Most adults aged 30+ who have developed noticeable sagging or fullness beneath the chin or jawline caused by ageing, weight fluctuations or genetics are suitable polynucleotide candidates. Indicators that PN injections may greatly improve your facial contour include:

  • Loose skin causing your jawline to appear lax or round rather than sharp and defined
  • Excess fatty deposits or bulges along the jaw and neck
  • Turkey wattles forming beneath the chin
  • Wrinkles or creases extending from the jaw down the neck

Provided you're in overall good health, polynucleotides can help sculpt loose or fallen jowls back into place. Always discuss your concerns and goals during a complimentary consultation.

Compare Polynucleotides Injections to Other Jowl Treatments

Other jowl-tightening options exist but compare as follows:





Minimal (1-3 days)

Gradual and natural-looking tightening over 6+ months

Thread lifts

1-5 days

Requires touch-ups annually; risks migration/extrusion



Addresses appearance but not long-term sagging



Temporary skin tightening without volume gain

Aqualyx injections


Targets submental fullness alone without jowl lift

Facelift surgery

1-2 weeks

Most effective but comes with drawbacks of surgery

For a minimally invasive solution yielding long-lasting contour refinement, polynucleotide injections are a premier choice.

Book The Best Polynucleotides Treatment for Jowls in London

Redefine your facial profile safely and naturally. Contact Injectual to book your polynucleotide consultation. Let our specialist assess your concerns and customise your treatment strategy. With polynucleotides, you can regain your jawline youth without facing significant downtime or risks. 

Frequently Asked Questions

Gradual improvement is visible within 4-6 weeks as collagen stimulates. Optimal contouring develops at 3 months and continues increasing for up to a year.

With maintenance 1-2 times per year, benefits can persist long-term. Without further treatment, visible tightening may gradually relax some over 12-18 months.

Yes, sagging or loose jawlines are just as common for men as women. Polynucleotides safely restore definition for all adult skin types.

The microinjections may cause minor pinpricks but are not typically painful. Any mild tenderness resolves within hours.

Most patients see optimal contouring after 3-6 sessions spaced 4 weeks apart. Annual touch-ups help maintain your sculpted jawline.

Yes, the technique also lifts dangling neck skin or "turkey wattles" when injections are performed along the jawline and into the neck.

While not adding substantial volume, it does tighten loose skin to create angularity. Fillers are best to simultaneously add fullness for thinning faces.

Schedule a consultation where your case can be fully assessed. Not all patients require surgery - PNs often yield natural-looking contouring.

While primarily tightening


Reduce appearance of sagging jowls

Return to work

Straight away.

Full recovery:

Straight away.

How Long does it last?

9-12 months.


5 Star reviews

Treatment by leading medics only

Plastic Surgeon founded

Complimentary consultation available


We just know you'll love your treatment with us so we're giving you £100 off your 1st treatment (over £300). Book your complimentary consultation below to start your aesthetic journey.



Book now



Our Injectual Practitioners

Founder Plastic Surgeon Dr. Veerle

Our founder Dr. Veerle, MD, FEBOPRAS, FCCP, is one of London's leading female plastic surgeons and is the co-founder of London’s holistic clinic, Tempus Belgravia. As her favourite motto is 'To be the best you need to learn from the best', Dr. Rotsaert has been travelling the world on the hunt for the world's leading techniques. Her and her peers' knowledge and skill have been used to create 5 proprietary techniques that will be used in all INJECTUAL clinics and by all injectors.

As founder of Injectual, Dr Rotsaert’s knowledge and understanding of both the surgical and non-surgical landscape is invaluable, and her commitment to helping enhance her patients’ lives continues to inspire.

Book Now

Aesthetic Doctor Thivos

Dr Thivos is a qualified doctor with a strong passion in aesthetic medicine. He graduated from one of the most prestigious medical schools in the world - Imperial College London. As well as his specialism in facial aesthetics, he has a background of working in medicine, surgery, psychiatry and A&E and has a strong background of anatomy and physiology.

Dr Thivos takes a holistic approach for bespoke treatment planning with his patients, aiming to enhance their features and bring beautiful results while maintaining natural and harmonised outcomes.

Specialties: Under Eye + Noses + Facial Feminisation/Masculinisation

Book now

Aesthetic Nurse Shantel

Shantel Noble is an Independent Nurse Prescriber (INP) and clinical trainer. Shantel has been working full time in aesthetics since finishing a masters qualification (level 7) in non-surgical aesthetic medicine in 2018. After finalising her Level 7, she decided to combine her passion for skin with teaching and become an aesthetics trainer for Harley Academy.

Shantel’s ethos is about achieving natural results, beautifying and restoring what was once had without changing your unique qualities.

Shantel prioritises patient safety, ethical practice and ensuring each person has a comfortable experience.

Specialties: Artistic Transformation + Profhilo + Skincare

book now


Dr Janine is an Aesthetic Doctor who graduated with a Bachelor of Dental Surgery from the University of Bristol in 2017 and has a Master’s qualification (the highest qualification for injectables) in non-surgical facial aesthetics. With a passion for teaching, Dr Janine thrives as a clinical trainer at the renowned Harley Academy.

Dr Janine is committed to maintaining facial balance and harmony, whilst creating a bespoke treatment plan. She also takes pride in treating patients holistically, thereby ensuring natural results that are both beautiful and elegant.

Specialties: Mid- and lowerface rejuvenation + Anti-wrinkle treatments

Book Now

aesthetic doctor nadia

Dr Nadia Taha, is a practicing GP, a General Medical Council registered Doctor and a Harley Academy trained Aesthetic Doctor. Having earned her medical degree from the University of Birmingham Medical School with a background in Plastic and Reconstructive Surgery, she believes in delivering excellence with her expertise in a safe and comfortable environment.

Dr Taha is passionate about helping clients and therefore, offers cutting-edge safe innovations and the best non-surgical treatments to achieve natural looking but profound results.

Specialities: Cheek, Nasolabial & Temple filler

Book now

Dr. Goziem - Aesthetic Doctor

Introducing Dr. Goziem Onuchukwu a highly experienced facial aesthetic practitioner known for her natural and stunning results. With prestigious academic qualifications from Barts and London, and a Masters in Aesthetic Medicine from Queen Mary's University of London, she brings a keen eye for detail and facial harmony. 

Dr. Goziem's approach emphasises the latest techniques and personalised care to address various skin concerns. Her warm and friendly demeanour ensures a comfortable experience for every client, while her commitment to safety and evidence-based treatments guarantees excellent results.

Specialities: Skin + Anti-wrinkle treatment 


Shima - Aesthetic Pharmacist

Shima Samivand is an Independent Pharmacist Prescriber (PIP) and a fully qualified Aesthetic Practitioner. Shima is particularly passionate about skin health and an advocate for medical-grade skincare.

Shima prides herself in providing personable advice supported by safe and evidence-based treatments and is a strong believer that subtle enhancements offer the best results. Having trained under some of the UK’s most respected aesthetic professionals, Shima combines the latest treatment methods with her patient centred approach to achieve her favourite aspect of the job - witnessing the confidence boost that non-surgical treatments offer to patients!

Specialties: Skin, lip enhancements and anti-wrinkle treatments

Book now

We just know you'll love your treatment with us so we're giving you £100 off your 1st treatment (over £300). Book your complimentary consultation below to start your aesthetic journey.

Where are we located? 

Our lovely Westbourne Grove studio is easily reachable by public transport from most central London locations and is located in the heart of the iconic Notting Hill. Most of our clients come from nearby neighbourhoods: Paddington, Hyde Park, Green Park, Bayswater, Soho, Kings Road, South Kensington, Kensington, Chelsea, Battersea, Fulham, Regents Park, Primrose Hill, St Johns Wood, Victoria, Mayfair, Knightsbridge, Belgravia, Fitzrovia, Holland Park, Earls Court, Highgate, West Brompton, Westminster, Islington, Hampstead, Hammersmith, Battersea or Nine Elms



TEL: +44 2039 519 115

Mon - Saturdays: 10am - 6pm