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FLEXIBLE FINANCING AVAILABLE

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Polynucleotides Treatment for Jowls
Polynucleotides Treatment for Jowls
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 5.0
Based on 2000+ customers

Polynucleotides Treatment for Jowls

£350.00
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The Future of Injectables

With age, loose, wrinkled skin often develops beneath our cheeks and jaws, commonly known as jowls. While a natural part of the ageing process, sagging jowls can make you appear tired or sad. If you've been feeling self-conscious about loose facial skin dragging your appearance down, it may be time to try polynucleotides - a cutting-edge non-invasive solution for restoring definition and volume to your jawline.

How Polynucleotides Tighten Sagging Jowls

Polynucleotides (PNs) work their anti-aging magic by stimulating your skin's natural collagen and elastin production from within. During treatment, these nucleotide complexes are carefully injected into the layers of skin beneath the chin and jawline where they signal fibroblasts to start generating new collagen fibres. Within weeks, this restored support structure begins lifting and tightening hanging jowls for a sculpted facial profile. By encouraging long-term collagen synthesis, polynucleotides provide gradual yet significant tightening of loose skin over a course of 6 months

What are the Key Benefits of Polynucleotide Injections for Jowls?

  • Gradual yet significant tightening: By stimulating collagen production, PNs lift and contour loose facial skin over 6-12 months for a rejuvenated jawline.
  • Natural-looking results: Unlike invasive procedures, PNs yield subtle reshaping that maintains your distinctive facial features and identity.
  • Minimal downtime: Most patients experience little tenderness or side effects, allowing an immediate return to regular activities.
  • Optional volume restoration: For thinning faces, PNs can be combined with fillers to both tighten sagging skin and add fullness.
  • Prevention of further laxity: Annual maintenance helps lock in benefits and prevents recurring looseness long-term.
  • Improved facial definition: Refreshed jawline contours restore a slim, sculpted oval appearance for your lower face.
  • Improved jowl-neck contour: Loose neck skin is also lifted to complete facial rejuvenation along the entire jawline angle.

Who is a Suitable Candidate for Polynucleotides Treatment for Jowls?

Most adults aged 30+ who have developed noticeable sagging or fullness beneath the chin or jawline caused by ageing, weight fluctuations or genetics are suitable polynucleotide candidates. Indicators that PN injections may greatly improve your facial contour include:

  • Loose skin causing your jawline to appear lax or round rather than sharp and defined
  • Excess fatty deposits or bulges along the jaw and neck
  • Turkey wattles forming beneath the chin
  • Wrinkles or creases extending from the jaw down the neck

Provided you're in overall good health, polynucleotides can help sculpt loose or fallen jowls back into place. Always discuss your concerns and goals during a complimentary consultation.

Compare Polynucleotides Injections to Other Jowl Treatments

Other jowl-tightening options exist but compare as follows:

Treatment

Downtime

Results

Polynucleotides

Minimal (1-3 days)

Gradual and natural-looking tightening over 6+ months

Thread lifts

1-5 days

Requires touch-ups annually; risks migration/extrusion

Radiofrequency

Immediate

Addresses appearance but not long-term sagging

Ultrasound

Immediate

Temporary skin tightening without volume gain

Aqualyx injections

Immediate

Targets submental fullness alone without jowl lift

Facelift surgery

1-2 weeks

Most effective but comes with drawbacks of surgery


For a minimally invasive solution yielding long-lasting contour refinement, polynucleotide injections are a premier choice.

Book The Best Polynucleotides Treatment for Jowls in London

Redefine your facial profile safely and naturally. Contact Injectual to book your polynucleotide consultation. Let our specialist assess your concerns and customise your treatment strategy. With polynucleotides, you can regain your jawline youth without facing significant downtime or risks. 


Treatment FAQ's

Q: How quickly will I see results from polynucleotide injections for jowls?

Gradual improvement is visible within 4-6 weeks as collagen stimulates. Optimal contouring develops at 3 months and continues increasing for up to a year.

Q: How long do polynucleotide injection results for jowls typically last?

With maintenance 1-2 times per year, benefits can persist long-term. Without further treatment, visible tightening may gradually relax some over 12-18 months.

Q: Can men also benefit from polynucleotide injections for jowls?

Yes, sagging or loose jawlines are just as common for men as women. Polynucleotides safely restore definition for all adult skin types.

Q: Is there much discomfort from polynucleotide injections for jowls?

The microinjections may cause minor pinpricks but are not typically painful. Any mild tenderness resolves within hours.

Q: How many polynucleotide injection treatments for jowls are needed?

Most patients see optimal contouring after 3-6 sessions spaced 4 weeks apart. Annual touch-ups help maintain your sculpted jawline.

Q: Can polynucleotide injections for jowls improve loose neck skin too?

Yes, the technique also lifts dangling neck skin or "turkey wattles" when injections are performed along the jawline and into the neck.

Q: Are polynucleotide injections for jowls effective for thin/gaunt facial types?

While not adding substantial volume, it does tighten loose skin to create angularity. Fillers are best to simultaneously add fullness for thinning faces.

Q: How do I know if polynucleotide injections for jowls are right for me?

Schedule a consultation where your case can be fully assessed. Not all patients require surgery - PNs often yield natural-looking contouring.

Q: Can polynucleotide injections for jowls improve jowl fullness as well?

While primarily tightening
What To Expect
Your polynucleotide treatment begins with a consultation to assess skin laxity, jowl positioning and facial balance. The injections are placed strategically along the jawline and submental area to stimulate collagen and elastin from within. Results develop gradually over several weeks, with continued skin tightening and improved definition for up to six months.
Downtime
Polynucleotide injections for jowls involve minimal downtime, making them ideal for busy lifestyles. Mild redness, swelling or tenderness at the injection sites may occur but typically settles within 24 to 72 hours. Most patients return to normal activities the same day with no disruption.
Our Approach
Injectual delivers doctor-led polynucleotide treatments using advanced injection techniques tailored to the jawline and lower face. Our approach focuses on skin regeneration, collagen stimulation and natural contour refinement rather than artificial lifting. Every treatment plan is customised following a detailed facial assessment to ensure precise, long-lasting results.
Treatment Areas

Designed for results you can see and feel

We aim to standardise, democratise and modernise medical aesthetics, ensuring the highest level of expertise, integrity and safety.

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Injectual Practitioners

Your safety is our priority. At Injectual, you will only ever be treated by highly qualified medical professionals, including Surgeons, Doctors, and Specialist Nurses.
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DR VEERLE ROTSAERT

Dr. Veerle Rotsaert, MD, FEBOPRAS, FCCP, is one of London’s most accomplished female plastic surgeons and a leading authority in advanced injectables. As co-founder of Tempus Belgravia and Injectual, she is renowned for her dual mastery in complex surgical procedures and cutting-edge non-surgical techniques, a rare combination that ensures her patients achieve harmonious, natural results.

Guided by her philosophy “To be the best, you need to learn from the best”, Dr. Rotsaert has trained under the most celebrated surgeons and aesthetic experts worldwide. Her global expertise has contributed to the creation of five proprietary injectable techniques, now used across all Injectual clinics and forming the gold standard for the brand’s protocols.

A graduate of the University of Leuven in Belgium, Dr. Rotsaert completed Plastic, Aesthetic and Reconstructive Surgery training at leading institutions around the world. She is a Fellow of the European Board of Plastic Surgeons, a Fellow of the College of Chest Physicians, and a member of both the British College of Aesthetic Medicine and the American Society of Plastic Surgery.

At Injectual, she plays a pivotal role in setting standards, training injectors, and innovating techniques that blend surgical precision with injectable artistry. Alongside treating patients, she develops skincare and treatment solutions designed to optimise and maintain results, supporting overall skin health.

Specialities: Complex facial and body surgery, surgical and non-surgical harmonisation, advanced injectable rejuvenation, and proprietary Injectual techniques.

Dr
Aesthetic Doctor Tony

Dr. Tony is a highly accomplished medical professional whose career blends academic excellence, clinical expertise, and a passion for education. A graduate of the University of Nottingham in Genetics and Biochemistry, he went on to complete his medical training at the University of Liverpool, graduating with merit.

With 8 years of experience in Surgical Specialties within the NHS and over 5 years in Aesthetic Medicine, Dr. Tony brings exceptional depth of medical knowledge and technical skill to every treatment. He is widely respected in the aesthetics industry, not only for his advanced clinical capabilities but also for his dedication to raising industry standards and innovating treatment approaches.

At Injectual, Dr. Tony is one of the principal training forces, playing a pivotal role in setting clinical protocols and quality benchmarks. His expertise ensures that every treatment performed under the Injectual name meets the highest standards of safety, efficacy, and ethics — reinforcing the clinic’s position as a leader in aesthetic medicine.

Alongside his work at Injectual, Dr. Tony is an Aesthetics Trainer for a large, nationally recognised training academy, where he teaches medical practitioners to become safe, confident, and highly skilled injectors. His approach blends scientific precision with artistic understanding, making him a sought-after mentor and thought leader in the field.

Internationally, Dr. Tony is recognised as an authority in masculinisation treatments and in the care of transgender and non-binary patients, delivering results that are affirming, empowering, and aligned with each individual’s goals. His work in this area is respected for its sensitivity, artistry, and deep anatomical expertise, helping patients feel seen, understood, and celebrated.

Dr. Tony offers a comprehensive range of treatments, from anti-wrinkle injections and dermal fillers to advanced injectable skincare (e.g., Profhilo, polynucleotides), microneedling, chemical peels, and holistic skincare consultations.

Specialities: Non-surgical nose jobs, skin boosters, masculinisation, transgender and non-binary patient care, and advanced skincare.

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Aesthetic Pharmacist Zain

Zain Ali, MPharm, is an internationally recognised force in the world of facial feminisation — a practitioner celebrated for his ability to combine scientific precision with aesthetic artistry. A dynamic pharmacist with a fresh and highly individualised approach to aesthetics, Zain seamlessly blends his deep pharmaceutical expertise with an unwavering passion for advanced skincare and injectable innovation.

After earning his Master’s degree in Pharmacy (MPharm) in 2018 and qualifying as an independent prescriber, Zain honed his expertise through years in luxury skincare before making his mark in aesthetics in 2021. His practice is defined by a meticulous understanding of facial anatomy, a refined artistic eye, and a commitment to enhancing natural beauty — particularly for women seeking elegant, harmonious feminisation.

Renowned for staying at the cutting edge of industry advancements, Zain specialises in anti-wrinklespolynucleotides (including the signature Injectual Polynucleotide Cocktail), skin boosters, and medical-grade skincare. His approach is grounded in evidence-based techniques and an innate sense of proportion, ensuring results that are both transformative and natural.

At Injectual, Zain is a key innovator and trendsetter, continuously elevating treatment standards and inspiring peers in the industry. Patients travel from far and wide for his expertise, knowing they are in the hands of a practitioner whose skill and precision have made him a respected name well beyond the UK.

Specialities: Facial feminisation, Injectual Polynucleotide Cocktail, skin boosters, anti-wrinkle treatments, and medical-grade skincare.

Dr
Aesthetic Doctor Nina 

Dr. Nina Cunning, MBChB, BSc (Med), is a distinguished aesthetic practitioner and skilled injector whose career seamlessly bridges advanced medical expertise with refined aesthetic artistry. She holds a Bachelor of Science in Medicine from The University of St Andrews and a Bachelor of Medicine and Bachelor of Surgery (MBChB) from The University of Glasgow — a foundation that underpins her meticulous, evidence-based approach to patient care.

With a background in Head and Neck Surgery, Dr. Cunning undertook prestigious specialist training followed by an intensive two-year fellowship in Robotic Head and Neck Surgery in London. This highly technical field demanded unparalleled anatomical knowledge, precision, and surgical dexterity — qualities that now define her aesthetic practice and set her apart as a practitioner of exceptional calibre.

Dr. Cunning is also deeply immersed in the global aesthetics community, regularly participating in international conferences and advanced training programmes. Her commitment to staying at the forefront of innovation ensures her patients benefit from the latest, safest, and most effective techniques available worldwide.

Known for her bespoke treatment planning, Dr. Cunning designs each aesthetic journey around the individual, marrying clinical skill with an intuitive understanding of beauty and proportion. Her warm, personable manner allows patients to feel at ease, while her artistry delivers results that are both transformative and natural.

Specialities: Advanced facial contouring, lip enhancements, polynucleotides, and The Injectual Polynucleotide Cocktail.

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Aesthetic Nurse Robyn

Nurse Robyn is a highly accomplished Aesthetic Nurse with over nine years of experience delivering an extensive range of aesthetic treatments. With a strong foundation in both clinical nursing and cosmetic procedures, she has developed a reputation for combining medical precision with an artist’s eye, consistently achieving results that enhance natural beauty while boosting her clients’ confidence.

Proficient in advanced injectable techniques — including anti-wrinkle treatments, dermal fillers, and skin boosters — as well as state-of-the-art skin rejuvenation therapies, Nurse Robyn approaches every treatment with meticulous attention to detail. Her ethos is built on listening deeply to each patient’s needs, engaging in thoughtful consultation, and creating bespoke treatment plans that reflect their unique features and aspirations.

Renowned for her delicate touch and ability to deliver subtle yet impactful transformations, Nurse Robyn is particularly sought after for her work in under-eye enhancement and lip augmentation. Her compassionate, personable manner ensures that every patient feels comfortable, informed, and confident in their treatment journey.

Specialities: Under-eye enhancement, lip filler, advanced injectables, and skin boosters.

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Aesthetic Nurse Lydia

Nurse Lydia is a highly skilled Registered Nurse Prescriber and accomplished aesthetic practitioner at Injectual, renowned for her ability to deliver regenerative, skin-transforming treatments that are as subtle as they are powerful. With a deep passion for skin health and an artistic approach to aesthetic medicine, Lydia guides her patients through transformative skin journeys that elevate natural beauty and restore youthful radiance.

Holding a prestigious Level 7 Diploma in Clinical Aesthetic Injectable Therapies, Lydia has trained under internationally recognised consultant plastic surgeons, ensuring every patient benefits from the highest standards of safety, precision, and artistry. Her expertise spans polynucleotides (including advanced under-eye rejuvenation), exosome therapymicroneedlinglip enhancement, and anti-wrinkle treatments — allowing her to design comprehensive, multi-modal plans that address both immediate concerns and long-term skin vitality.

Lydia is particularly admired for her knowledge and flair in skin regeneration, using cutting-edge innovations such as exosomes to stimulate repair, improve texture, and promote a luminous, healthy complexion. Her patients value not only her technical skill but also her compassionate, consultative approach, ensuring they feel informed, comfortable, and confident throughout their treatment journey.

Specialities: (Under-eye) polynucleotides, exosome therapy, microneedling, artistic transformations, lip enhancement, anti-wrinkle treatments, and advanced skin rejuvenation.

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Dr. Fiori Teklebrhan

Dr. Fiori Teklebrhan, MBBS, BSc (Hons), Dist. Aesthetic Medicine, is an exceptionally skilled aesthetic doctor and one of Injectual’s most experienced injectors, renowned for her meticulous technique, artistic precision, and dedication to natural yet impactful results. Holding a First-Class Honours BSc in Psychology, a Bachelor of Medicine and Bachelor of Surgery (MBBS), and a Distinction in Aesthetic Medicine from Queen Mary University of London, she brings a rare combination of medical excellence, psychological insight, and aesthetic artistry to her work.

Since specialising full-time in aesthetics in 2022, Dr. Fiori has already performed over 1,500 injectable treatments, earning a reputation as a trusted expert for patients seeking elegant, balanced transformations. Her advanced skill set spans anti-wrinkles, dermal fillers, Sculptra, skin boosters, and polynucleotides, enabling her to address both structural enhancement and regenerative skin health with equal expertise.

With a background in breast surgery and anatomy teaching, Dr. Fiori’s deep understanding of facial structure and proportion allows her to deliver treatments that are not only beautiful but anatomically precise. She is particularly renowned for midface and lower face sculpting, where her work restores youthful contours while maintaining the patient’s natural individuality.

Her commitment to ethical, patient-centred care ensures that each treatment plan is bespoke, aligning with the patient’s goals and focusing on subtle enhancement, longevity, and skin vitality. Passionate about regenerative treatments, Dr. Fiori champions innovative approaches — from Sculptra to polynucleotides — to achieve radiant, healthy skin and lasting confidence.

Specialities: Midface and lower face sculpting with dermal fillers, volumisation and collagen stimulation with Sculptra, skin brightening with polynucleotides and skin boosters, and advanced anti-wrinkles treatments.

Real Results from Our Community

Injectual Testimonials
Frey
Treatment
Insta-Injectual Facial, Polynucleotides eye, 3 areas of anti-wrinkles
Review

Injectual is my absolute go-to for a total skin transformation; the combination of microneedling, a PRX peel, and targeted anti-wrinkles perfectly balanced my features. Adding polynucleotides under the eyes was a game-changer for a refreshed look. I couldn't be happier with these professional, medical-led results

Book Your Treatment

Begin your transformation today.

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Jack Nuzum
Treatment
Polynucleotides and Exosomes
Review

The medical team at Injectual completely transformed my skin prep with a strategic protocol of exosomes and polynucleotides. My complexion has never looked clearer or more luminous—it's the ultimate cellular-level glow that left me feeling perfectly rested and camera-ready for my event!

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Begin your transformation today.

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Shakeel Murtaza
Treatment
Polynucleotides Eye
Review

I've been struggling with stubborn dark circles for a while, so I visited INJECTUAL for a Salmon DNA skin boost. The Polynucleotides treatment was a total game-changer for my under-eyes. Just look at my before and after

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Amy Hancock
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Jalupro and Lip Flip
Review

The professional, medical-led team in Notting Hill made me feel completely at ease for my holiday glow-up. After the Jalupro Super Hydro treatment, my skin feels incredibly hydrated and firm, with a radiant, youthful dewiness that is perfect for the season!

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Begin your transformation today.

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Gabz Tooma
Treatment
Anti-Wrinkle and Lip Flip
Review

I am so impressed with Dr. Nina's expertise; she achieved a perfectly natural look that smoothed my skin without any 'frozen' feel. The subtle lip flip gave me that extra boost of confidence I was looking for, proving that a little tweak really does make all the difference!

Book Your Treatment

Begin your transformation today.

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Eva
Treatment
Polynucleotides and Lip Filler
Review

Zain is a true professional; the combination of Polynucleotides and lip filler left my skin looking revitalised and my lips perfectly defined. The results are incredibly natural and have given me a refreshed, glowing look that I absolutely love

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Led by renowned Plastic Surgeon Dr Veerle Rotsaert, our team of medical practitioners each have over five years’ experience in aesthetic medicine.

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FAQ's

Your questions, answered. Can’t find what you’re looking for? Ask us below.

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What makes the INJECTUAL process so special?

We’re so glad you asked: even before you step into INJECTUAL we want to make sure you’re taken care of. Our customer service team is always available to answer any questions you may have and put you at ease. We like to think that INJECTUAL is more than just a clinic, it’s an immersive experience. From our state of the art waiting room, to our signature INJECTUAL techniques, to the highest trained professionals in the field, we want to make sure everything we do is to the highest standard. We offer the best in pain management techniques, including numbing cream and nitrous oxide. We also offer specialty in-studio aftercare (complimentary, of course) including a recovery room where you can relax for as long as you want with a LED light treatment that aids recovery and will leave your skin with an extra bit of glow. Come in and see for yourself what makes INJECTUAL special.

Do I need to avoid anything before the procedure?

Before your treatment, please avoid alcohol for 24h before the procedure, as this can thin the blood and increase the risk of bruising. Blood-thinners, like Ibuprofen, ginseng and Omega 3, should also be avoided. Make sure you DO have food and drink liquid on the day of your procedure to avoid light headedness.

Post treatment tips?

Try your best to not touch the treated area for 3 hours, avoid heavy lifting and intense physical exercise for at least 24 hours. Avoid excessive amounts of alcohol and sodium as this could lead to swelling. If you do experience some minor swelling, you can apply a cold compress for 15 minutes every hour. Paracetamol can help with any pain management. Be sure to sleep face up if you had a facial procedure. If you require any more assistance or help after your procedure, our expertly trained staff is always on hand to answer your questions and offer medical advice.

What are your opening times?

Clinic Hours: 
Monday: 10:00 – 18:00
Tuesday: 10:00 – 18:00
Wednesday: 10:00 – 20:00
Thursday: 10:00 – 18:00 (with extended hours until 20:00 on selected Thursdays — please enquire)
Friday: 10:00 – 20:00
Saturday: 10:00 – 18:00
Sunday: Closed

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